Cardiovascular risk factors in young Czech females with polycystic ovary syndrome.
نویسندگان
چکیده
BACKGROUND Polycystic ovary syndrome (PCOS) could be associated with a variety of signs of metabolic syndrome. The aim of our study was to compare the cardiovascular risk factors in PCOS women and in a control group selected from a random population sample. METHODS AND RESULTS 50 PCOS women with a mean (+/-SD) age of 30.7 +/- 4.2 years, and 335 controls with a mean age of 29.9 +/- 3.1 years selected from a random population sample of nine districts of the Czech Republic were compared for basic anthropometric characteristics, blood pressure, plasma lipids and fasting glucose. PCOS women had a significantly higher body mass index (BMI). After adjusting for BMI, PCOS women had higher blood pressure and LDL-cholesterol, and lower HDL and HDL-cholesterol/total ratio. Arterial hypertension was more prevalent in PCOS women than in controls. There was no difference in the prevalence of impaired fasting glucose between both groups. Impaired glucose tolerance was found in 11.8% of PCOS women. Diabetes mellitus was more frequent in PCOS families. CONCLUSIONS Czech PCOS women, even in their thirties, show a significantly worse cardiovascular risk profile than a control group selected from a random population sample. The differences cannot be explained by obesity.
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Analysis of CRP, Vitamin D and Metabolic Factors in Non-obese Patients with Polycystic Ovary Syndrome: a Cross Sectional Study in Imam Khomeini Hospital, Ahvaz
Background and Objectives: The polycystic ovary syndrome (PCOS) is one of the most common diseases diagnosed in women of childbearing age which is associated with increased risk of metabolic complications, including cardiovascular disease. Increasing C-reactive protein (CRP) as an inflammatory factor is common in these patients. In addition, vitamin D deficiency is quite common among females wi...
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عنوان ژورنال:
- Human reproduction
دوره 18 5 شماره
صفحات -
تاریخ انتشار 2003